Butranep - Your Solution for Melasma and Hyperpigmentation: non-invasive, safe and 99% effective

Key Features of Butranep:

1. What is Butranep?

Traditionally, Tranexamic acid is used to treat and prevent bleeding associated with increased fibrinolysis (Prostatectomy and bladder surgery, Menorrhagia, Epistaxis, Conisation of the cervix, Traumatic hyphaema; Management of dental extraction in haemophiliacs, Hereditary angioneurotic oedema, etc)

Since 2010, numerous clinical trials and studies explore the role of Tranexamic acid in treating melasma with oral administration, topical application, meso injection.

Butranep is an oral solution containing Tranexamic Acid at a concentration of 100 mg/ml. It is designed for the treatment of melasma, a common skin condition characterized by dark, discolored patches on the skin. Butranep offers a non-invasive, safe, and effective option for managing melasma and hyperpigmentation.

How It Works:

Tranexamic Acid works by inhibiting the activation of plasminogen, which in turn reduces the production of melanin, the pigment responsible for dark spots. This helps in lightening the affected areas and improving overall skin tone.

2. How to use Butranep?

Through analysis of Aleksandra L et al (2021), Tranexamic Acid with high doses in the range of 500-1500 mg provides good melasma treatment effects and causes few unwanted effects. The optimal treatment dose is 1000 mg. 

Take the ampoule orally.

3. What are the outstanding advantages?

Non-invasive therapy is always first-line treatment for melasma. 𝐁𝐔𝐓𝐑𝐀𝐍𝐄𝐏, an oral solution of 100 mg/ml tranexamic acid in a convenient 10 ml ampoule, offers outstanding advantages and efficacy.

Clinically Proven: Supported by studies showing significant improvement in melasma symptoms with consistent use. 

📌 Zining Xu et al (2024): This randomized, prospective, controlled study compared Tranexamic acid in acne rosacea with the traditional method of doxycycline plus topical hyaluronic acid. The Tranexamic acid group demonstrated significantly greater and faster improvements in clinical erythema assessment and investigator’s global assessment scores compared to the traditional treatment group. This proves that adding oral Tranexamic Acid to traditional therapies leads to rapid improvements in papulopustular rosacea. Read more: https://www.dermatologytimes.com/view/adding-oral-tranexamic-acid-to-traditional-therapies-led-to-rapid-improvements-in-papulopustular-rosacea

📌 Christian Diehl (2019), Use of tranexamic acid in melasma: Following the review of the currently available literature concerning the use of tranexamic acid in melasma, it appears that this active ingredient permits achieving a good efficacy in this indication where there is no satisfactory therapy, with minor side effects. 

https://www.researchgate.net/publication/336637610_Use_of_tranexamic_acid_in_melasma

Read more on:

[1] https://www.dermatologytimes.com/view/tranexamic-acid-melasma 

[2] https://www.dermatologytimes.com/view/closer-look-tranexamic-acid-melasma

 

4. What should be noticed while using Butranep?

Side Effects: Common side effects may include mild irritation, nausea, or headache. Seek medical advice if you experience severe side effects such as vision changes or signs of a blood clot.

Contraindication:

• Hypersensitivity to tranexamic acid.

• History of thromboembolic disease.

• Patients undergoing anticoagulant therapy.

• Severe renal impairment (due to the risk of drug accumulation).

• Cases of central nervous system surgery, central nervous system bleeding, subarachnoid hemorrhage, or other types of cerebral hemorrhage.

• Fibrinolysis follows disseminated intravascular coagulation (DIC) except in patients with strong fibrinolytic system activation during severe bleeding; history of seizures; intrathecal, intraventricular, or intracranial injection; use of hormonal contraceptives.

Storage: Store the ampoules in a tight container at a temperature below 30oC, avoid light and moisture, 

 

Conclusion

Choose Butranep Tranexamic Acid for an effective and scientifically-backed solution to manage melasma. Trust in the quality and efficacy of Butranep, brought to you by CPC1 Hà Nội, a Leading Pharmaceutical Technology.