Adrenaline (as Adrenaline tartrate) 1mg/ml
Ampoule 1ml, 5ml
Solution for injection
Treat of cardiovascular arrest, anaphylactic shock and cardiocirculatory distress with states of anaphylactic, hemorrhagic, traumatic shock,
infectious or secondary to cardiac surgery
Posology
Severe hypersensitivity reactions, anaphylactic shock
IM Injection:
Adults: The usual dose is 500 micrograms (0.5ml of adrenaline 1/1000). If necessary, this dose may be repeated several times at 5-minute intervals according to blood pressure, pulse and respiratory function.
Half doses of adrenaline may be safer for patients who are taking amitriptyline, imipramine or a beta blocker.
Paediatric population
The following doses of adrenaline 1/1,000 are recommended:
Age | Dose |
Over 12 years | 0.5 mg IM (0.5ml 1:1000 solution) |
6 - 12 years | 0.3 mg IM (0.3ml 1:1000 solution) |
6 months - 6 years | 0.15 mg IM (0.15ml 1:1000 solution) |
Under 6 months | 0.01mg/kg IM (0.01ml/kg 1:1000 solution) |
If necessary, these doses may be repeated at 5-15 -minute intervals according to blood pressure, pulse and respiratory function.
Elderly
The dosage is the same as for younger adults but particular caution is required when administering adrenaline to elderly patients (see section 4.4).
Renal impairment
Adrenaline should be used with caution in patients with severe renal impairment (see section 4.4).
Method of Administration
Adrenaline Injection BP. 1/1000 (1mg/ml) may be administered undiluted by S.C. or IM injection. In the shocked patient, the intramuscular route is recommended as absorption from the intramuscular site is more rapid and reliable than from the subcutaneous site.
A small volume syringe should be used.