Metoclopramid Hydrochlorid 5 mg/5ml
Sodium benzoate (E211)
Citric acid monohydrate (E330)
Sodium citrate (E331)
Saccharin sodium (E954)
Lemon flavour 13499 (containing propylene glycol (E1520), natural flavouring
substances and flavouring preparation)
Purified water
Oral solution
Adult population
Metoclopramide is indicated in adults for:
• Prevention of delayed chemotherapy induced nausea and vomiting (CINV).
• Prevention of radiotherapy induced nausea and vomiting (RINV).
• Symptomatic treatment of nausea and vomiting, including acute migraine induced
nausea and vomiting. Metoclopramide can be used in combination with oral
analgesics to improve the absorption of analgesics in acute migraine.
Paediatric population
Metoclopramide is indicated in children (aged 1-18 years) for:
• Prevention of delayed chemotherapy induced nausea and vomiting (CINV) as a
second line option.
Adult population
The recommended single dose is 10 mg, repeated up to three times daily.
The maximum recommended daily dose is 30 mg or 0.5mg/kg body weight.
The maximum recommended treatment duration is 5 days.
Prevention of delayed chemotherapy induced nausea and vomiting (CINV)
(paediatric patients aged 1-18 years)
The recommended dose is 0.1 to 0.15 mg/kg body weight, repeated up to three times
daily by oral route. The maximum dose in 24 hours is 0.5 mg/kg body weight.